Are NPB's supplements safe to take with my current medication?Updated 3 months ago

We know many of you juggle prescription drugs—like blood-pressure pills, diabetes medications, or statins—and it’s natural to worry about side effects. Supplements, such as Nitric Oxide Flow (NPB's L-arginine and L-citrulline amino acid formula), can support healthy blood pressure levels, but combining them with medications requires careful coordination with your healthcare team.  

Below is information you can review and discuss with your medical professional:

1. Always Consult Your Doctor First

Only a licensed medical professional can assess your full health picture. Show them our Supplement Facts label and discuss:

• Your current medications (including anticoagulants, antihypertensives, and diabetes medications)

• Your personal health goals, including any wish to reduce reliance on synthetic drugs

Dr. Suzanne Steinbaum, cardiologist and author of Dr. Suzanne Steinbaum’s Heart Book, teaches that natural and alternative approaches can complement medical therapy—but only under a physician’s oversight. webmd.com

2. Understand the Risk of Overlapping Effects

Natural supplements sometimes boost or blunt the action of drugs.

• Hypotension risk (too-low blood pressure): Nitric Oxide Flow works by widening blood vessels. If added on top of an ACE inhibitor or beta-blocker without adjusting your dose, your blood pressure could dip too far—causing dizziness, lightheadedness, or fainting.

Even smart doctors struggle to predict all drug–nutrient interactions, warns Dr. Mark Hyman, functional medicine physician. Always review every supplement, herb, and vitamin with your prescriber. “A number of supplements can enhance, diminish or negate a prescription drug in ways that can be consequential and unpredictable,” according to Brittany Langdon, PharmD. Yale New Haven Health

3. Never Stop Prescription Medications Abruptly

Quitting a prescribed drug “cold turkey” can trigger a rebound effect—your body may overcorrect, spiking blood pressure or blood sugar to dangerous levels. Always taper under medical supervision.

Dr. Aseem Malhotra, a well-known cardiologist and advocate for lifestyle medicine, emphasizes the importance of reducing the reliance on synthetic medications and exploring effective natural alternatives, particularly when supported by strong evidence. However, he strongly advises against abruptly stopping any prescribed medications without a proper, doctor-guided weaning plan.  TheGuardian

4. Leverage Expert-Led Monitoring Plans

A thoughtful, personalized plan—with frequent check-ins—lets you safely integrate supplements and track real results:

1. Baseline measurement: Record blood pressure, heart rate, or blood sugar before starting.

2. Introduce supplement: Add one product at a time (e.g., Nitric Oxide Flow) while keeping your medication dose constant.

3. Re-check in 1–2 weeks: Adjust your drug dosage only with your doctor’s approval.

4. Ongoing review: Continue monthly or as directed by your cardiologist or endocrinologist.

Dr. Robert Lustig, professor of pediatric endocrinology at UCSF, reminds us that supplements can amplify or counteract prescription effects—making careful tracking essential to avoid unwanted swings.

5. How to Proceed Safely

• Bring your supplements (bottle and label) to every medical appointment.

• Ask about gradual weaning: If your doctor agrees, you might slowly lower drug doses as your body responds—never on your own.

• Schedule follow-up checks: Monitor vital signs or lab values every 1–2 weeks during periods of change.

Reminder: These statements have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional for advice on any medical condition or before making changes to your prescription medications.